Completed Research Project
Recovery of musculoskeletal and cardiopulmonary changes in children in remission from cancer
Investigators: Laird K, Monterosso L & Johnston K.
Funding: Leukaemia Foundation of WA, New Investigator Research Grant ($10,012)
Administering institution: Edith Cowan University
Abstract: This study will focus on children and adolescents who have had treatment for cancer, primarily those who have had lymphoma or leukaemia. Cancer is an uncommon disease in childhood and early adolescence when compared with the incidence in adults. Childhood cancer survival rates have witnessed dramatic improvements over the past three decades due to the substantial progress that has been achieved in paediatric oncology therapy. Such improvements in survival rates have lead to increasing awareness of and investigation into the complications and long term side effects of cancer and its treatment.
There is extensive research investigating the impact and late effects of paediatric oncology therapy. Body systems such as heart, lungs and liver can be affected. However, the impact of effects on strength and physical fitness (in particular aerobic fitness) of children following oncology therapy, and in turn their ability to return to school, previous activity levels and to fully participate in home and community life, lacks substantial evidence and thus warrants further exploration. For the purpose of this study the focus will be primarily on the musculoskeletal and cardiopulmonary systems. This will help to identify if a decrease in physical fitness such as decrease joint movement, muscle strength and endurance and aerobic exercise capacity as well as obesity, which will impact upon a child's ability and ease to return to school and previous level of physical activity. It is also important to consider how such physical impairments and activity limitations, if present, may impact upon the psychosocial well being and quality of life of the child. A pilot study completed in 2005 identified that some children and adolescents who have completed oncology therapy within the past 18 months are weaker and less fit than other children. A study has now commenced to see how quickly children regain their fitness and return to usual activities.
